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Incidence of Alzheimer’s Disease and the Urgent Need for Innovative Treatment Approaches.

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Brookmeyer (2007, 2010) reports the worldwide prevalence of Alzheimer’s disease to be 26.6 million, which by 2050, is expected to quadruple

This would mean that “1 in 85 persons worldwide will be living with the disease. It is estimated that about 43% of prevalent cases need a high level of care, equivalent to that of a nursing home. If interventions could delay both disease onset and progression by a modest 1% per year, there would be nearly 9.2 million fewer cases of the disease in 2050, with nearly the entire decline attributable to decreases in persons needing a high level of care.”  (Corrada, Brookmeyer, et.al.  “Dementia incidence continues to increase with age in the oldest old: The 90+ study”, Annals of Neurology;Volume 67, Issue 1, pages 114–121, January 2010 and Brookmeyer, E. Johnson, K. Ziegler-Graham, H. Arrighi. “Forecasting the Global Burden of Alzheimer’s disease, Alzheimer’s and Dementia, Volume 3, Issue 3, Pages 186-191R, 2013.

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