Research on Reducing Risk and Slowing Progression of Mild Cognitive Impairment and Alzheimer’s Disease.

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Improvement of Episodic Memory in Persons with Mild Cognitive Impairment and Healthy Older Adults: Evidence from a Cognitive Intervention

Source: Belleville, Sylvie (et al.) Dementia Geriatric Cognitive Disordors 2006;22:486-499.

A 2006 study by Belleville, et al., examined “subjects with mild cognitive impairment [who] are at risk for developing Alzheimer’s disease.” (25., p 1.) This study looked at the effect of cognitive training on memory. Cognitive training improved delayed free recall of lists and name memory.  This effect was highly significant, and important because these are the core impairments in patients with MCI and the ones most likely to deteriorate further. Improvement in this impairment relates directly to functional status and are the improvements that need to be achieved in order to delay progression to dementia. [bold added] Interestingly, the improvement in delayed recall of lists in MCI patients was great enough to make their post-training status similar to that of normal participants before training.


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